My method of fitting saddles is "keep adjusting until it feels right" but usually the adjustment is up/down [in very tiny increments] with the seat post or forward/back on the rails. If it is a new saddle it may take a few miles before your butt and the saddle to become friendly with one and other.
Might be the saddle. Even an expensive one needs to fit you. Before you go crazy on adjustment make sure it is a male friendly in the important places. Everyone's butt and bones are different, you need to find one that fits your anatomy.I ran into that myself, just because it was $110 saddle didn't mean it was right for me. A $49 Specialized saddle did the trick for me.
It does take some patience and riding to get it just right. Also as you ride those "areas" seem to get tougher. Movements forward and the tilt should be done in very small increments. You will be amazed at how different 1/8 inch feels. you may also be suprised that raising the front (tilt back) helps some. Also when you will find the padded riding shorts work well. When you put them on, lift your junk. A gel pad for your seat is something else to try. Still, there is nothing that works better than saddle time.
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